Scientist, Analytical Development and Quality Control

Location: San Francisco
Posted on: June 23, 2025

Job Description:

Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease. Position Nurix Therapeutics is seeking a talented scientist to join the Analytical Development and Quality Control group. This role supports analytical and QC activities from clinical to commercial CMC development and manufacturing. The ideal candidate will have a strong background in analytical chemistry, with expertise in operating and troubleshooting HPLC and dissolution methods, as well as instrumentation for characterizing drug products. Experience with method development, method validation, and data interpretation is highly desirable. This position involves conducting method development and troubleshooting activities internally, as well as overseeing method development, validation, and testing at external CDMO/CRO partners. The Scientist will work closely with other departments to ensure seamless integration of analytical and QC activities. This position is based at Nurix headquarters in San Francisco, CA. Key responsibilities Design and conduct complex analytical experiments with consistency across several analytical platforms while employing appropriate controls. Manage method development, method validation, QC testing, and reference standard management activities internally and at CDMOs/CTLs. Perform laboratory-based experiments to optimize drug product analytical methods. Conducts complex experimental troubleshooting. Process, evaluate, and interpret experimental data, drawing conclusions based on results. Maintain detailed laboratory notebooks accurately. Present data at team and cross-functional meetings. Critical review of data, protocols, reports, specifications, and other documentation. Trending stability data and establishing retest periods/shelf life using statistical methods. Works collaboratively, cross-functionally, and within the team to achieve program goals. Travel up to 10%. Additional responsibilities as required. Qualifications Advanced degree in a relevant discipline (Chemistry, Pharmaceutics, or related field). BS degree with 10 years, MS degree with 6 years, or Ph.D. with 2 years of industrial CMC experience. Expertise in HPLC and dissolution method development is essential. Experience in analytical method development and validation. Experience managing stability programs, reference standards, and retest/expiry. Familiarity with ICH guidelines, cGMPs, and pharmacopeial chapters. Ability to critically interpret data and articulate technical concepts in multidisciplinary settings. Ability to ensure assigned activities are completed to the satisfaction of project timelines. Strong interpersonal skills that foster collaboration within and outside of the organization. Ability to travel domestically and internationally. Fit with Nurix Culture and Values Strong team orientation; highly collaborative Solutions and results-oriented focus Hands-on approach; resourceful and open to diverse points of view Application Process Nurix is an Equal Opportunity Employer offering a competitive salary and benefits package. Applicants should be legally entitled to work for any employer in the US. Note to Employment Agencies: Please do not forward any agency resumes. Nurix will not be responsible for fees related to unsolicited resumes. Nurix Therapeutics, Inc. is committed to protecting and respecting your privacy and personal information, including information collected by Nurix when you apply for a job with Nurix or in the course of your employment with Nurix. By applying for a position at Nurix, you agree to our collection and use of personal information as described in our Privacy Policy ( https://www.nurixtx.com/privacy-policy/ ).

Keywords: , San Bruno , Scientist, Analytical Development and Quality Control, Science, Research & Development , San Francisco, California