Life Science Research Professional 2
Company: Stanford Medicine
Location: San Bruno
Posted on: May 16, 2022
Job Description:
Stanford University is seeking a Life Science Research
Professional 2 to perform more complex functions and activities
involved in defined translational projects, and independently
conduct a portion of the research project(s) at Cancer Correlative
Science Unit (CCSU), providing Translational Research associated
with CCT clinical trials.
The Mackall laboratory works on enhancing the effectiveness of
existing cancer immunotherapies and on developing novel
immunotherapies. We focus primarily on using genetically engineered
T cells to treat cancer, with an emphasis on chimeric antigen
receptors (CARs). CARs are non-natural receptors, created using
synthetic biology, that endow T cells with the capacity for
antigen-specific, MHC-unrestricted killing. As part of CCSU's
operations, the team performs Biomarker analyses and immunological
monitoring of the patients treated with these novel CAR-T and other
cellular therapies testing in clinical trials. This position will
be directly involved in the design, development and execution of
novel molecular technology using qPCR, ATAC-seq, ddPCR and DNA/RNA
sequencing technology to perform translational research on the
clinical specimen that are bio-banked. The candidate will also be
involved in the generation of documents (Standard Operating
Procedures SOPs, batch records, etc.) to support. Other job duties
include maintaining excellent lab records, report to supervisor,
effectively communicate experimental results to the team and the
principal investigator, and train other lab personnel on basic
experimentation techniques.
Duties include:
- Independently conduct a portion of the Translational research
project(s) as assigned. Make recommendations on experimental design
and/or research direction to principal investigator.
- Independently conduct complex (lab and/or field) experiments to
gather data for a portion of a major research project.
- Interpret and analyze results
- Develop and validate research protocols where appropriate
protocols are not described in the literature or where modification
or adaptation of standard procedures and protocols is
required.
- Participate in multidisciplinary teams across different
faculties or schools.
- Perform ongoing literature review to remain current with new
procedures and related research; apply to ongoing research and
development of new protocols.
- Contribute substantively to the preparation of papers for
publication, especially in the results section, and to publication
of findings. Present ongoing work to colleagues and/or academic
conferences.
- Serve as a technical resource for other research staff and
train as applicable.
- Oversee the daily activities of the laboratory including lab
maintenance; maintain lab stock, manage chemical inventory and
safety records, and provide general lab support as needed. May
assist with purchasing laboratory equipment.
*- Other duties may also be assigned
DESIRED QUALIFICATIONS:
Direct experience performing qPCR, ddPCR and ATAC-seq is an
advantage. Experience performing DNA and RNA isolation. Molecular
assay experience is an advantage. Knowledge in excel, Prism or
similar for data analyses is considered highly preferred.
EDUCATION & EXPERIENCE (REQUIRED):
Bachelor's degree in related scientific field and two years of
relevant work experience; or Master's degree in a related
scientific field.
KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):
- Comprehensive understanding of scientific principles.
- General computer skills and ability to quickly learn and master
computer programs, databases, and scientific applications.
- Strong analytical skills and excellent judgment.
- Ability to maintain detailed records of experiments and
outcomes.
- Ability to work under deadlines with general guidance is
essential.
- Excellent organizational skills and demonstrated ability to
accurately complete detailed work.
PHYSICAL REQUIREMENTS*:
- Frequently stand, walk, twist, bend, stoop, squat, grasp
lightly, use fine manipulation, grasp forcefully, perform
desk-based computer tasks, use telephone, write by hand, lift,
carry, push and pull objects weighing over 40 pounds.
- Occasionally sit, kneel, crawl, reach and work above shoulders,
sort and file paperwork or parts.
- Rarely climb, scrub, sweep, mop, chop and mix or operate hand
and foot controls.
- Must have correctible vision to perform duties of the job.
- Ability to bend, squat, kneel, stand, reach above shoulder
level, and move on hard surfaces for up to eight hours.
- Ability to lift heavy objects weighing up to 50 pounds.
- Ability to work in a dusty, dirty, and odorous
environment.
- Position may require repetitive motion.
*- Consistent with its obligations under the law, the University
will provide reasonable accommodation to any employee with a
disability who requires accommodation to perform the essential
functions of his or her job.
WORKING CONDITIONS:
- May require working in close proximity to blood borne
pathogens.
- May require work in an environment where animals are used for
teaching and research.
- Position may at times require the employee to work with or be
in areas where hazardous materials and/or infectious diseases are
present.
- Employee must perform tasks that require the use of personal
protective equipment, such as safety glasses and shoes, protective
clothing and gloves, and possibly a respirator.
- May require extended or unusual work hours based on research
requirements and business needs.
WORK STANDARDS:
- Interpersonal Skills: Demonstrates the ability to work well
with Stanford colleagues and clients and with external
organizations.
- Promote Culture of Safety: Demonstrates commitment to personal
responsibility and value for safety; communicates safety concerns;
uses and promotes safe behaviors bases on training and lessons
learned.
- Subject to and expected to comply with all applicable
University policies and procedures, including but not limited to
the personnel policies and other policies found in the University's
Administrative Guide, .
As an organization that receives federal funding, Stanford
University has a COVID-19 vaccination requirement that will apply
to all university employees, including those working remotely in
the United States and applicable subcontractors. To learn more
about COVID policies and guidelines for Stanford University Staff,
please visit
Additional Information
- Schedule: Full-time
- Job Code: 4952
- Employee Status: Regular
- Pay Grade: G
- Department URL:
- Requisition ID: 94230 As an organization that receives federal
funding, Stanford University has a COVID-19 vaccination requirement
that will apply to all university employees, including those
working remotely in the United States and applicable
subcontractors. To learn more about COVID policies and guidelines
for Stanford University Staff, please visit
Keywords: Stanford Medicine, San Bruno , Life Science Research Professional 2, Other , San Bruno, California
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