Life Science Professional 1
Company: Stanford Medicine
Location: San Bruno
Posted on: November 22, 2021
The Ma Laboratory in the Stanford University School of Medicine
Department of Cardiothoracic Surgery, Division of Pediatric
Surgery, is seeking to hire a full-time Life Science Research
Professional 1 as an independent research fellow in our lab.
We currently are focusing on two main projects:
- Ex vivo modeling of the atrioventricular valve in single
- Congenital Heart Disease Simulator
Ex vivo Modeling of the AV valve in SVP
We are using an ex vivo heart simulator to model AV valve function
in single ventricle physiology and optimize surgical repair
strategies. We then intend to translate into both large animal
models (i.e., pigs) and clinical settings. We can use this
simulator to measure variables such as hemodynamics (via integrated
flow probes & pressure sensors), valve leaflet motion & coaptation
(via high-speed videography), morphometrics (via echocardiography),
and strain sensing on chordae tendineae. Please see the following
publication for an example of our prior work with the ex vivo heart
Congenital Heart Disease Simulator
We are currently developing an MRI compatible mock circulatory loop
and cardiac phantoms to simulate common congenital heart lesions.
We will use integrated pressure and flow sensors to capture
hemodynamic data and magnetic resonance velocimetry measurements to
capture microscopic flow patterns (locations of stagnation &
reverse flow and the shape of the jets). We will answer questions
regarding cannulation strategies for patients with complex
anatomies, ventricular assist device (VAD) approaches for a failing
Fontan physiology and patient-VAD mismatches.
We believe this is an excellent gap year opportunity for
individuals who plan to apply to medical school or graduate
programs. If you are interested in this position, or have any
questions, please send an email to James Lee at
firstname.lastname@example.org. Please attach your current CV.
- Plan approach to experiments in support of research projects in
lab and/or field based on knowledge of scientific theory.
- Independently conduct experiments; maintain detailed records of
experiments and outcomes.
- Apply the theories and methods of a life science discipline to
interpret and perform analyses of experiment results; offer
suggestions regarding modifications to procedures and protocols in
collaboration with senior researcher.
- Review literature on an ongoing basis to remain current with
new procedures and apply learnings to related research.
- Contribute to publication of findings as needed. Participate in
the preparation of written documents, including procedures,
presentations, and proposals.
- Help with general lab maintenance as needed; maintain lab
stock, manage chemical inventory and safety records, and provide
general lab support as needed.
- Assist with orientation and training of new staff or students
on lab procedures or techniques.
*- Other duties may also be assigned
- Disclaimer: A strong candidate does not need to possess ALL of
the following qualifications, but should have at least some of
- Significant prior research experience, preferably in a
cardiovascular-related field. However, the ability to think
critically and carry out experiments independently is
- Background in mechanical engineering, electrical engineering,
biomedical engineering, or bioengineering.
- Experience with MATLAB, CAD programs (Solidworks), 3D printing
(FDM, SLA, DLP, and/or DLS), and/or other rapid prototyping
- Experience with control systems and signal processing. Specific
experience with sensors and actuators is particularly desirable.
Experience with LabView or similar software is strongly
- If coming from an engineering-oriented background, basic
knowledge of anatomy/physiology are recommended.
- Basic surgical hand skills, including suturing, handling basic
instruments, and performing dissections.
- Advanced writing and reading ability, which could be
demonstrated via prior publications.
- Knowledge of cardiovascular/cardiopulmonary anatomy &
physiology. Some developmental biology knowledge may also be
beneficial as our work focuses on congenital heart diseases.
- Ability to lead a project, including reading/synthesizing
literature, designing experiments based on the literature,
conducting experiments, performing data analysis, and writing up
final results, is highly desirable.
EDUCATION & EXPERIENCE (REQUIRED):
Bachelor's degree in related scientific field.
KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):
- General understanding of scientific principles. Demonstrated
performance to use knowledge and skills when needed.
- Demonstrated ability to apply theoretical knowledge of science
principals to problem solve work.
- Ability to maintain detailed records of experiments and
- General computer skills and ability to quickly learn and master
computer programs, databases, and scientific applications.
- Ability to work under deadlines with general guidance.
- Excellent organizational skills and demonstrated ability to
accurately complete detailed work.
CERTIFICATIONS & LICENSES:
- Frequently stand, walk, twist, bend, stoop, squat, grasp
lightly, use fine manipulation, grasp forcefully, perform
desk-based computer tasks, use telephone, write by hand, lift,
carry, push and pull objects weighing over 40 pounds.
- Occasionally sit, kneel, crawl, reach and work above shoulders,
sort and file paperwork or parts.
- Rarely climb, scrub, sweep, mop, chop and mix or operate hand
and foot controls.
- Must have correctible vision to perform duties of the job.
- Ability to bend, squat, kneel, stand, reach above shoulder
level, and move on hard surfaces for up to eight hours.
- Ability to lift heavy objects weighing up to 50 pounds.
- Ability to work in a dusty, dirty, and odorous
- Position may require repetitive motion.
*- Consistent with its obligations under the law, the University
will provide reasonable accommodation to any employee with a
disability who requires accommodation to perform the essential
functions of his or her job.
- May require working in close proximity to blood borne
- May require work in an environment where animals are used for
teaching and research.
- Position may at times require the employee to work with or be
in areas where hazardous materials and/or infectious diseases are
- Employee must perform tasks that require the use of personal
protective equipment, such as safety glasses and shoes, protective
clothing and gloves, and possibly a respirator.
- May require extended or unusual work hours based on research
requirements and business needs.
- Interpersonal Skills: Demonstrates the ability to work well
with Stanford colleagues and clients and with external
- Promote Culture of Safety: Demonstrates commitment to personal
responsibility and value for safety; communicates safety concerns;
uses and promotes safe behaviors based on training and lessons
- Subject to and expected to comply with all applicable
University policies and procedures, including but not limited to
the personnel policies and other policies found in the University's
Administrative Guide, http://adminguide.stanford.edu .
- Schedule: Full-time
- Job Code: 4945
- Employee Status: Regular
- Pay Grade: E
- Department URL: http://ctsurgery.stanford.edu/
- Requisition ID: 89522 As an organization that receives federal
funding, Stanford University has a COVID-19 vaccination requirement
that will apply to all university employees, including those
working remotely in the United States and applicable
subcontractors. To learn more about COVID policies and guidelines
for Stanford University Staff, please visit
Keywords: Stanford Medicine, San Bruno , Life Science Professional 1, Other , San Bruno, California
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